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Medical hair restoration in the literal sense includes the hair loss treatment which depends upon the use of medicines. Unusual hair loss both in men and women is caused by the alterations in the androgen metabolism. Androgen is a male hormone which has a major role to play in regulation of hair growth or hair loss. The dermal papilla is the most important structure in a hair follicle which is responsible for hair-growth. It is the dermal papilla, the cell of which divides and differentiates to give rise to a new hair follicle. The dermal papilla is in direct contact with blood capillaries in the skin to derive the nutrients for the growing hair follicle. Research has shown that dermal papilla got many receptors for androgens and there are studies which have confirmed that males have more androgenic receptors in dermal papilla of their follicles as compared to females. The metabolism of androgen involves an enzyme called 5 alpha reductase which combines with the hormone androgen(testosterone) to form the DHT (Dihydro-testosterone). DHT is a natural metabolite of our body which is the root cause of hair loss. Proper nutrition is critical for the maintenance of the hair. When DHT gets into the hair follicles and roots (dermal papilla), it prevents necessary proteins, vitamins and minerals from providing nourishment needed to sustain life in the hairs of those follicles. Consequently, hair follicles are reproduced at a much slower rate. This shortens their growing stage (anagen phase) and or lengthens their resting stage (telogen phase) of the follicle. DHT also causes hair follicle to shrink and get progressively smaller and finer. This process is known as miniaturization and causes the hair to ultimately fall. DHT is responsible for 95% of hair loss. Some individuals both men and women are genetically pre-disposed to produce more DHT than the normal individuals. DHT also creates a wax-like substance around the hair roots. It is this accumulation of DHT inside the hair follicles and roots which is one of the primary causes of male and female pattern hair loss. Blocking the synthesis of DHT at molecular level forms the basis for the treatment of MPHL ( male pattern hair loss) and FPHL female pattern hair loss). There are many natural DHT blockers and a number of drugs which are used for medical hair restoration. Let us see the main drugs which are available for medical hair restoration in men and women. Minoxidil Minoxidil has the distinction of the first drug being used for promoting the hair restoration. This medical hair restoration treatment drug was used earlier as an oral antihypertensive drug, but after its hypertrichosis (excessive body hair) effects were noticed, a topical solution of the drug was tested for its hair growing potential. Minoxidil was then approved as medical hair restoration treatment drug for men by the US Food and Drug Administration (FDA) in 1988 as a 2% solution, followed by 5% solution in 1997. For women, the 2% solution was approved in 1991. Though 5% solution is not approved for women, it is used as a medical hair restoration treatment by many dermatologists worldwide. Both solutions are available without a prescription in the US. Mechanism of action Minoxidil is thought to have a direct mitogenic effect on epidermal cells, as has been observed both in vitro in vivo. Though the mechanism of its action for causing cell proliferation is not very clear, minoxidil is thought to prevent intracellular calcium entry. Calcium normally enhances epidermal growth factors to inhibit hair growth, and Minoxidil by getting converted to minoxidil sulfate acts as a potassium channel agonist and enhances potassium ion permeability to prevent calcium ions from entering into cells. Thought the exact action of minoxidil preventing the formation of DHT has not been shown but the drug has been shown to have a stabilizing effect on the hair loss. The result of the drug takes about few months time to be evident since it is the time which is necessary for restoring the normal growth cycle of hair fibers. Use of Minoxidil has approved by FDA for men (Norwood II-V) and women (Ludwig I-II ) older than 18 years. It is used as a medical hair restoration treatment either for frontal or vertex scalp thinning. It brings about an increase in density which is mostly caused by conversion of miniaturized hairs into terminal hairs rather than a stimulated de novo re-growth. The hair loss becomes stabilized after continued use of drug, which takes about a year’s time for the medical hair restoration treatment to show its complete results. Hair loss restoration treatment with 0.05% betamethasone dipropionate and 5% topical minoxidil are found to be superior to minoxidil alone. Topical minoxidil is very well tolerated and adverse effects are mainly dermatologic. The most frequent adverse effect is an irritant contact dermatitis. Though minnoxidil does not have any effect on blood pressure, it should be used with caution in patient with cardiovascular diseases. It is also contraindicated in pregnant and nursing mothers. Finasteride The drug finasteride was earlier used as treatment for prostate enlargement, under the medical name Proscar. But in 1998, it was approved by FDA for the Medical hair loss restoration in MPHL. Mechanism of Action Medical hair restoration treatments with Finasteride depends upon its specific action as an inhibitor of type II 5α-reductase, the intracellular enzyme that converts male hormone androgen into DHT (Dihydro Testosterone). Its action results in significant decrease in serum and tissue DHT levels in even in concentration as low as 0.2mg. Finnasteride is able to stabilize hair loss in 80% of patient with Vertex hair loss and in 70% of patients with frontal hair loss. Most of these patients are able to grow more hair or retain the ones they have. The peculiar thing about Propecia is that its effect is more pronounced in crown area than in the front. The hair that grow after the medical hair restoration treatments are better in texture and are thicker, more like the terminal hair. The best thing about medical hair restoration treatment with the finnasteride is that it is well tolerated and has minimal side effects. Sexual dysfunction (decreased sex drive, erectile dysfunction, and decreased semen volume) are observed in about 3.8% of cases. But these side-effects subside within few months of Medical hair restoration treatments or disappear within a week’s time as soon as the treatment is stopped. It generally requires about 6 to 12 months for the m edical hair restoration treatment to be apparent but the side effects appear earlier. So even after the medicine is stopped, there is no possibility of loosing the hair that has been gained, but the side effects are sure to disappear. Many hair restoration surgeons find Propecia (finasteride) to act as an excellent adjunct to the surgical hair restoration. There are several benefits of this kind of combination therapy. As the Medical hair restoration with Propecia brings about a hair re-growth in the crown area, it has a complementary action; it allows the surgeon to have more donor hair to be available for frontal hair transplant and design the hairline at his own will. Since finasteride has no effect in the frontal area of the scalp, it does not have any interference with the surgical hair restoration. Combination Therapy There are reports which say that use of finasteride and topical minoxidil combination therapy as a Medical hair restoration treatment is of more advantage in cases of mild to moderate MPHL. Further studies are in progress. Many hair restoration doctors have already started the use of combination therapy in order to obtain better hair growth. Anti Androgen Therapy For women with hyperandrogonism( with increased levels of androgen) who do not respond well to minoxidil, antiandrogen therapy is another option of Medical hair restoration. In UK the most commonly used anti-androgen for women is CPA (cyproterone acetate), which is used in combination with ethinyl-estradiol. However, in United States, where CPA is not available, the aldosterone antagonist spironolactone is the alternative choice of hair restoration doctors. Flutamide Medical hair restoration with flutamide has shown improvement as hair loss restoration treatment in women with hirsutism. For hyperandrogenic premenopausal women, flutamide is a better medical hair restoration agent than both the CPA or finestride. Hair loss restoration management is a structured process which depends upon many factors along with the medical hair restoration. For more details on the topic you can refer to section medical hair restoration or article on male pattern hair loss or female pattern hair loss at our site hairtransplantadvice.com. penis enlargment without pills vimax male penis enlargement penile enlargement testimonials penile enlargement surgeries do penis enhancement pills work penis enlargement excersizes herbal penis elargement pills where to buy vigrx penile enlargement secret
The Complications associated with Primary Pulmonary Hypertension can lead to fatal consequences in patients afflicted by this progressive lung disorder. However, there is no reason for despair. The situation may be grave but a variety of treatments are now available, aiming at prevention or even curing of Primary Pulmonary Hypertension-related Complications. A serious Complication may be blood clots. Blood clot formation where there is no need for it can turn fatal. If there are clots in the small arteries of the lungs then this can pose a threat by disturbing the already narrowed or blocked blood vessels, thereby terminating normal blood circulation to the lungs. This undesirable clotting or coagulation of blood can be remedied by the use of anti-coagulants. However, it must be remembered that anti-coagulants have their own risks and benefits, which need to be carefully considered by a doctor prior to administration. Fluid build-up in the body may be another complication. Two kinds of edemas- pedal edema (fluid accumulation in legs) and ascites (fluid accumulation in abdomen) are among such Primary Pulmonary Hypertension Complications. Pulmonary edema may also develop as a complication, whereby the lungs fill with accumulated fluid. This may even prove to be fatal, as the accumulated fluid can hamper the proper exchange of oxygen and carbon dioxide in the lungs. As medication for such edema, diuretics are helpful. A less-fluid, low-sodium diet may also manage the risks of such complications. The enlargement of the heart’s right ventricle, leading to its functional failure, is among the most serious of the Primary Pulmonary Hypertension Complications. This might even lead to a complete failure of the heart. Several drug treatments come in aid of these complications- digoxin therapy, vasodilators, calcium channel blockers; endothelin receptor antagonists and oxygen therapies are carried out as treatment. It may be that a lung transplant proves a workable solution for the prevention or treatment of Primary Pulmonary Hypertension Complications. penis enlargement fact homemade penis enargement manual penis enhancement exercise prosolution enlargement penis pill vimax natural penis enlagement technique free penis enlargement technique manual penile enlargment exercise penile enlargement secret
Vitamins are essential for the growth and development of the human body. Vitamins are found in natural foods. A good diet virtually ensures an abundant supply of vitamins. Sometimes due to certain medical conditions, the body is deprived of certain vitamins, leading to a deficiency. Vitamin A deficiency is a common disease in poorer parts of the world and causes night blindness. Vitamin A is found in fish, liver and green vegetables. Failure to consume sufficient quantities of meat, milk or milk products leads to a deficiency in Vitamin B12. This deficiency causes megaloblastic anemia and, if severe enough, can result in irreversible damage to the nerves, liver and intestinal tract. A person can experience hallucinations, memory loss, eye disorders and anemia. Vitamin C, found in green vegetables, berries and citrus fruits, helps prevent infection, enhances immunology and can help prevent cancer. A lack of Vitamin C can cause anemia, bleeding gums, muscle degeneration and blood clots. A deficiency in Vitamin D affects the bones, heart, kidneys and the thyroid gland. Common symptoms are irregular heartbeat, Osteoporosis and brittle and fragile bones. Vitamin D also enhances the immune system. Vitamin E is found in vegetable oils, whole grains, spinach and milk. A deficiency may cause an enlargement of the prostate gland, gastrointestinal disease, impotency and decreased circulation. Vitamin E helps prevent cancer and cardiovascular diseases. Vitamin K plays an important role in the formation of bones and blood clotting. It also converts glucose into glycogen for storage in the liver. A lack of Vitamin K leads to a low platelet count and poor blood clotting. Folic acid is essential for the formation of red blood cells and is vital for normal growth and development. Folic acid is found in beans, beef, barley and chicken, amongst others. A deficiency of folic acid causes depression, anxiety and birth defects in pregnant women. Vitamin deficiency can treated by recommending dietary regulations, oral supplements, or by injections. Oral supplements are useful for those unable to consume food rich in vitamins. Injections are useful for persons with diseases that prevent absorption of fat-soluble vitamins. pennis enlargement before and after photo free penis enlagement tip penis enargement video best enlargment exercise penis vimax penis enlargement pills review homemade penis elargement natural penis enlarement exercise home penis enlargment penile enlargement secret
Here you will learn all about misconceptions about penis size and how you can be perfectly happy with the size of penis you have. There are many misconceptions about penis size and here we separate fact from fiction. Currently penis size is big business there is more than $1 billion per year spent on vitamins, creams, pumps etc No one knows penis size better than condom manufacturers. Here are some facts on penis size from their research: •Research shows that more than 70 percent of men have penises that measure between 5 and 7 inches when erect. A penis is considered abnormally small only if it measures less than 3 inches when erect, and even then it might not matter •The above size statistics are true for all the races of mankind. The concept that black men have a large penis while Japanese have small ones is totally false. •A recent Dutch study of 375 sexually active women who had recently given birth suggests that the surveys are accurate — to a point. Seventy-nine percent of the women said that penis length is unimportant, and 69 percent of them said the same about penis girth. •Exercise and food supplements can enlarge the size of your penis is totally false. Penis size and your partner Your partner is the best judge of size, but try to remember when you were young and in high school. .. To make money, and feed on men’s insecurity about their penis size and possibility they may have a small penis many products are sold that simply dont work. How to increase small penis 4 methods guaranteed not to work! There are several methods recommended to increase penis size and surprise, surprise, none of them work. Here are 4 examples. 1.Stretching, and squeezing - sometimes known as jelquing. These are exercises that are supposed to be performed each day for an indefinite period of time. Although they appear safer than other methods, they can lead to severe scar formation, and disfigurement. The only result gained is a soft penis that has a somewhat larger appearance. This method has no affect on the erect penis. 2.Vacuum pumps and other devices. Because pumps force blood into the penis, making it swell, they can sometimes be useful in the treatment of impotence. This may create an illusion of a larger penis, and the results are seldom permanent. Rather, repeated damages the elastic tissue in the penis, finally producing softer erections, or no erections at all. 3.Stretching with penile weights. This technique is dangerous, and very likely to cause permanent damage to your penis. 4.Pills, lotions, and hormone creams. These can contain vitamins, minerals, herbs. They sometimes have chemicals similar to Viagra and Cialis. They also can contain hormones such as testosterone. Note that there is no evidence that it or any other substance can increase penis size in adult men. The opposite is rather the case. Another method to increase a small penis size is cosmetic surgery. In these surgical procedures, please note that EVERY professional medical society have all issued policy statements against cosmetic surgical procedures to enhance the penis. The results can be catastrophic. To lengthen a penis, the surgery typically involves cutting the suspensory ligament that attaches the penis to the pubic bone and moving skin from the abdomen to the penile shaft. As the suspensory ligament stabilizes and gives an upward tilt to an erect penis, after surgery, the penis will not longer be able to achieve this tilt. Such surgery can cause the penis to wobble, erect at strange angles, and more often than not, cause unpleasant side-effects. On the negative side, after various types of cosmetic penile enhancement surgery, some men have had to undergo additional correction operations to address the deformities caused by the original procedure. Some of the negative effects of this type of surgery are scarring, fat clumps, low-hanging penis, loss of sensitivity, bumps, lumps, shorter penis, and hair on the base of the penis. Other complaints include persistent pain, impotence, and urinary incontinence So, unless your partner (s) remarks that something is wrong, follow the old adage of “not fixing what isn’t broken”. On the other hand, take some time to understand your partner's physical, emotional needs and desires, and you may do a great deal more to improve your sexual relationship than would changing the size of your penis. The myth of the small penis is exactly that and most women are more interested in a loving partner more than penis size. Of course, there are exceptions but generally men should not be concerned over size.